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Swindells (1995) developed a method, DETECTIVE, for identification of domains in protein structures based on the idea that domains have a hydrophobic interior.

DIMACS Workshop on Protein Domains: Identification, Classification and Evolution February 27-28, 2003 DIMACS Center, CoRE Building, Rutgers University

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK *

Biophysical Journal 91:670-685 (2006) © 2006 The Biophysical Society Dynamic Protein Domains: Identification, Interdependence, and Stability Semen O.